منابع مشابه
Plasma concentrations of pancuronium during predetermined intensities of neuromuscular blockade.
The plasma concentrations of pancuronium were monitored during i.v. infusions of the relaxant in dogs. Pancuronium was administered at rates which maintained the degree of neuromuscular blockade at three predetermined levels. The concentrations of the drug in the blood were consistent for any one animal but showed considerable overlap for the three levels of paralysis between animals. Concentra...
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Oxycodone is commonly used to treat severe pain in adults and children. It is extensively metabolized in the liver in adults, but the maturation of metabolism is not well understood. Our aim was to study the metabolism of oxycodone in cryopreserved human hepatocytes from different age groups (3 days, 2 and 5 months, 4 years, adult pool) and predict hepatic plasma clearance of oxycodone using ...
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A B S T R A C T To determine the plasma epinephrine thresholds for its metabolic and hemodynamic actions and plasma epinephrine metabolic clearance rates, 60-min intravenous epinephrine infusions at nominal rates of 0.1, 0.5, 1.0, 2.5, and 5.0,ug/min were performed in each of six normal human subjects. These 30 infusions resulted in steady-state plasma epinephrine concentrations ranging from 24...
متن کاملPlasma chromogen and the endogenous creatinine clearance.
One of the troubles of using the endogenous creatinine clearance to measure the filtration rate is that plasma and serum contain chromogens, other than creatinine, which give a colour with the Jaffe reaction. The creatinine can, however, be isolated by adsorption on Fuller's earth (Gaebler and Keltch, 1928) and subsequently eluted with the alkaline picrate used for colour production (Borsook, 1...
متن کاملConcordance Between Iothalamate and Iohexol Plasma Clearance.
To the Editor: Iohexol is regarded as an accurate filtration marker for measuring GFR. Recently, Soveri et al concluded that plasma clearance of iohexol could be considered a valid alternative to the gold standard, urinary clearance of inulin. Because inulin urinary clearance is cumbersome and costly, iohexol and iothalamate clearance have become popular in Europe and the United States, respect...
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ژورنال
عنوان ژورنال: British Journal of Anaesthesia
سال: 1980
ISSN: 0007-0912
DOI: 10.1093/bja/52.3.360